Symptoms of malignant pleural mesothelioma
Nonspecific dull chest or shoulder pain, shortness of breath, dyspnea, dry cough, fatigue, weight loss, digital clubbing, hypertrophic osteoarthropathy, superior vena cava syndrome, lymphadenopathy, chest wall masses, dysrhythmias, pleural effusion, pericardial effusion, ascites, or bowel obstruction due to spread to the peritoneal cavity may be seen. Chest wall pain is an important sign of chest wall involvement by tumor. Malignant pleural mesothelioma should be considered in any patient with either pleural effusion or pleural thickening, especially if chest pain is present.