Symptoms of Eosinophilic Granulomatosis with Polyangiitis
What are the major clinical features of Eosinophilic Granulomatosis with Polyangiitis
The below table lists the major clinical features of Eosinophilic Granulomatosis with Polyangiitis.
Major Clinical Features of EGPA
| Organ | Clinical Manifestations |
|---|---|
| Paranasal sinus | Acute or chronic paranasal sinus pain or tenderness, rhinitis (70%), polyposis, opacifications of paranasal sinus on radiographs |
| Lungs | Asthma (usually adult onset), patchy and shifting pulmonary infiltrates (70%), nodular infiltrates without cavitations, pleural effusions, and diffuse interstitial lung disease seen on chest radiograph. Pulmonary hemorrhage can occur. |
| Nervous system (60%–70%) | Mononeuritis multiplex or asymmetric sensorimotor polyneuropathy; rarely central nervous system or cranial nerve involvement |
| Skin (50%) | Subcutaneous nodules, petechiae, purpura, skin infarction, (they occur mainly during the vasculitic phase) |
| Joints (50%) | Arthralgias and arthritis (rare) |
| Gastrointestinal | Eosinophilic gastroenteritis (abdominal pain, bloody diarrhea), abdominal masses |
| Miscellaneous | Renal failure (uncommon), congestive heart failure, corneal ulcerations, panuveitis, prostatitis |
