Significance of conduction block in peripheral neuropathy

What is the significance of conduction block in peripheral neuropathy? 

Conduction block occurs only in certain limited acquired settings of acute reversible ischemic injury, compression-induced demyelination, and acquired demyelinative neuropathies but not in hereditary neuropathies, with one major exception—hereditary neuropathy with liability to pressure palsy (HNPP).

Clinically, conduction block is important because it implies a potentially reversible defect-causing weakness.


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