Role of MAO B inhibitors in Parkinsons Disease

What is the role of MAO B inhibitors in Parkinsons Disease? 

MAO B inhibitors include selegiline and rasagiline, which help to block the breakdown of dopamine in the brain, thus making more dopamine available.

These are modestly effective as symptomatic treatment for Parkinsons Disease and may have neuroprotective properties.

MAO B inhibitors are usually used as early monotherapy or as an add-on medication to drugs such as levodopa in more advanced Parkinsons Disease to decrease “off” time.

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