Role of EUS in sampling pancreatic cystic neoplasms

What is the role of EUS in sampling pancreatic cystic neoplasms? 

  • EUS with FNA can be used to obtain diagnosis in the case of suspected cystic neoplasms.
  • Additional analysis of aspirated fluid can also be of value, such as a mucin stain (positive in intraductal papillary mucinous tumor, mucinous cystadenoma, and mucinous cystadenocarcinoma), determination of amylase level (suggestive of a pseudocyst), and carcinoembryonic antigen (CEA) level (a high CEA level suggests the presence of mucinous cystadenoma with malignant potential, but a normal CEA level suggests the presence of a serous cystadenoma or pseudocyst with no malignant potential)
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