Rheumatic Syndromes Associated with Sarcoidosis
1. A patient with acute, inflammatory arthritis involving bilateral ankles should always be evaluated for sarcoidosis.
2. Majority of patients (95%) with sarcoidosis have thoracic involvement.
3. Most patients with sarcoidosis will not require medical therapy.
4. First-line treatment for severe manifestations of sarcoidosis includes corticosteroids; methotrexate is recommended if a patient fails to respond to, or is unable to taper corticosteroids.
5. Tumor necrosis factor α (TNFα) inhibitors may be effective for treatment-resistant sarcoidosis cases.
