Remitting relapsing articular symptoms due to chikungunya infection
Rarely, the arthralgia/arthritis can follow a chronic remitting-relapsing course, with symptoms persisting as long as six years following initial infection in some patients. Less commonly, a pattern of chronic persistent arthritis/arthralgia may develop. The proper laboratory assessment includes the detection of virus-specific antibodies (IgM and IgG).Treatment is generally supportive, but the use of hydroxychloroquine, methotrexate and even biologic DMARD therapy has been described in patients with persistent post-CHIK arthritis.
