What are the recommendations for vitamin D supplementation in older adults?
The 2010 Institute of Medicine recommendations for vitamin D supplementation are set at 600 IU/day for men and women aged 51 to 70 years and 800 IU/day for older individuals.
In 2010, the National Osteoporosis Foundation (NOF) recommended that older adults aged ≥ 65 years should have a serum 25(OH)D level of ≥30 ng/mL (75 nmol/L) to reduce risk for falls and fractures. Supplementation doses up to 800 to 1000 IU/day were recommended because of the lack of evidence for efficacy of higher doses. These recommendations are also supported by the International Osteoporosis Foundation (IOF) and the American Geriatrics Society (AGS).
The 2011 Endocrine Society clinical practice guidelines suggested maintaining a serum 25(OH)D level of ≥30 ng/mL (75 nmol/L) with vitamin D 2 or D 3 1500 to 2000 IU/day.
In 2012, the United States Preventive Services Task Force (USPSTF) reported that supplementation of 400 IU/day of vitamin D in combination with 1000 mg/day of calcium does not reduce fracture risk in noninstitutionalized, community-dwelling, asymptomatic adults without a previous history of fractures. It was further noted that there is a lack of evidence regarding the effectiveness of higher doses of vitamin D and calcium on incident fractures.