Prognosis of Sickle cell nephropathy
What is the prognosis of patients with SCN
• In general, patients with SCD have life expectancy reduced by 25 to 30 years.
• Patients with SCD and kidney failure: Median survival among patients with and without kidney failure is 29 and 51 years, respectively. Survival is substantially worse among patients with SCD and ESKD compared with their counterpart without the disease.
• Kidney transplant recipients: Although survival of transplant recipients with SCD is inferior to that of matched African American recipients without the disease, survival of SCD patients is comparable with that of matched diabetic patients. One-year graft survival exceeds 60% to 80%.