What are the primary manifestations of LEMS?
In LEMS, weakness and fatigability of proximal muscles, especially in the thighs and pelvic girdle, with depressed or absent tendon reflexes are the primary manifestations.
Muscle strength and/or reflexes may increase for a short while after exercise (postexercise facilitation and facilitation of reflexes).
Although ptosis may be present in LEMS, extraocular and bulbar muscles are minimally involved.
Mild autonomic dysfunction may be prominent in LEMS, manifesting primarily as dryness of the mouth.
