What are the potential complications of CPN?
There is a 1% to 2% risk of major complications. Neurologic complications include lower extremity weakness, parathesia, or paralysis. The artery of Adamkiewicz runs along the spine between T8 and L4, and perfuses the lower two thirds of the spinal cord. Spasm or thrombosis of this artery can lead to spinal cord ischemia. In addition, direct damage to the spinal cord or somatic nerves can cause neurologic deficits. Chronic gastroparesis or diarrhea may also occur. Bleeding, infection, and inadvertent organ puncture are also recognized complications.