What is the paramedian pontine reticular formation (PPRF)?
The Paramedian pontine reticular formation is a collection of cells lying in the pons adjacent to the nucleus of cranial nerve VI, and is an important center for horizontal gaze.
Efferent fibers from the PPRF project to the ipsilateral abducens (VI) nucleus, and to the contralateral oculomotor (III) nucleus through the MLF, stimulating both eyes to move horizontally.