Osteoarthritis with CPPD versus typical Osteoarthritis

Osteoarthritis with CPPD versus typical Osteoarthritis

What features suggest that a patient has OA with CPPD rather than typical OA?

OA with CPPD ( pseudo-OA ) is seen in approximately half of patients diagnosed with symptomatic chronic CPPD-associated arthropathy. The pattern of joint involvement may be different from that seen in primary OA, the degree of articular damage may be more severe, and disease course may be marked by intermittent episodes of inflammatory arthritis. Patients with CPPD presenting as pseudo-OA commonly have severe degenerative changes in the MCPs, radiocarpal joints, elbows, shoulders, and knees. Of these joints, only the knees are typically involved in primary OA. Therefore, a patient with OA in atypical joints should be evaluated for CPPD. Patients with pseudo-OA are treated with NSAIDs, analgesics, physical therapy, and joint surgery, similar to the therapy for primary OA.

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