What is the normal CT and MRI appearance of the spleen?
The normal spleen has homogeneous soft tissue attenuation on unenhanced CT, usually 5 to 10 HU less than liver, and appears slightly hypointense on T1-weighted images and hyperintense on T2-weighted images relative to liver.
It is typically less than 13 cm in craniocaudal dimension and has an average volume of ≈225 ml in adults. Splenic clefts are commonly seen, which are smooth curvilinear infoldings of the splenic surface without surrounding fluid
