Which is the most sensitive examination for detecting hemochromatosis?
MRI: Because many patients with hemochromatosis will develop cirrhosis and 25% will develop HCC, it is important to diagnose early.
US: US examination is normal despite iron deposition, unless underlying cirrhosis is present.
NCCT: Liver attenuation is typically more than 70 HU in hemochromatosis, compared with a normal level of approximately 45 to 60 HU.
MRI: More sensitive and specific than CT in detecting hemochromatosis. On MRI, the paramagnetic effects caused by iron deposition result in decreased T2-w and GRE signal intensity