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What are the most common causes of Acute tubulointerstitial nephritis?
The most common causes of Acute tubulointerstitial nephritis are classified as below:
- • Drugs
- • Infection
- • Autoimmune systemic diseases
- • Idiopathic
Drugs account for most Acute tubulointerstitial nephritis cases.
Drug-induced Acute tubulointerstitial nephritis is not dose dependent, but rather is an idiosyncratic reaction. Repeat exposure to the same drug or a closely related agent can lead to recurrence of the disease process
Drugs Causing Acute Tubulointerstitial Nephritis
| Antimicrobial Agents Acyclovir Ampicillin a Amoxicillin Aztreonam Carbenicillin Cefaclor Cefamandole Cefazolin Cephalexin Cephaloridine Cephalothin Cephapirin Cephradine Cefoxitin Cefotetan Cefotaxime Ciprofloxacin Cloxacillin Colistin Cotrimoxazole a Erythromycin Ethambutol Foscarnet Gentamicin Indinavir Interferon Isoniazid Lincomycin Methicillin a Mezlocillin Minocycline Nafcillin Nitrofurantoin a Norfloxacin Oxacillin a Penicillin G a Piperacillin Piromidic acid Polymyxin acid a Quinine RIFAMPICIN a Spiramycin a Sulfonamides Teicoplanin Tetracycline Vancomycin | NSAIDs, Including Salicylates Alclofenac Azapropazone Aspirin Benoxaprofen Diclofenac Diflunisal a Fenclofenac Fenoprofen Flurbiprofen Ibuprofen Indomethacin Ketoprofen Mefenamic acid Meloxicam Mesalazine (5-ASA) Naproxen Niflumic acid Phenazone Phenylbutazone Piroxicam Pirprofen Sulfasalazine Sulindac Suprofen Tolemetin Zomepirac Analgesics Aminopyrine Antipyrine Antrafenin Clometacin a Floctafenin a Glafenin a Metamizol Noramidopyrine Anticonvulsants Carbamazepine Phenobarbital Phenytoin a Valproate sodium | Diuretics Chlorthalidone Ethacrynic acid Furosemide a Hydrochlorothiazide a Indapamide Tienilic acid a Triamterene a Others Allopurinol a Alpha-methyldopa Azathioprine Bismuth salts Captopril a Carbimazole Chlorpropamide a Cyclosporine Cimetidine Clofibrate Clozapine D-penicillamine Fenofibrate a Gold salts Griseofulvin Interferon Interleukin-2 Omeprazole Phenindione a Phenothiazine Phenylpropanolamine Probenecid Propranolol Propylthiouracil Ranitidine Streptokinase Sulphinpyrazone Warfarin |
Drugs most commonly involved are shown in capital letters.
a Drugs that can induce granulomatous acute interstitial nephritis.
