Major causes of AKI in cancer patients

Major causes of AKI in cancer patients

What are the major causes of AKI in the patients with malignancy?

AKI may occur by at least two mechanisms:

  • 1. A complication of a particular cancer treatment:
    • a. TLS
    • b. Drug-induced nephropathy
    • c. Post-transplant-related kidney diseases
    • d. Surgical procedures
  • 2. Related to the neoplasm itself
    • a. Renal cell cancer
    • b. Anatomic obstruction due to a metastatic lesion or obstructing mass
    • c. Myeloma/amyloid affecting the kidney

Patients with AKI and malignancy have a worse prognosis than AKI without malignancy.

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