Major causes of AKI in cancer patients
What are the major causes of AKI in the patients with malignancy?
AKI may occur by at least two mechanisms:
- 1. A complication of a particular cancer treatment:
- a. TLS
- b. Drug-induced nephropathy
- c. Post-transplant-related kidney diseases
- d. Surgical procedures
- 2. Related to the neoplasm itself
- a. Renal cell cancer
- b. Anatomic obstruction due to a metastatic lesion or obstructing mass
- c. Myeloma/amyloid affecting the kidney
Patients with AKI and malignancy have a worse prognosis than AKI without malignancy.