What is lymphangitic carcinomatosis?
Lymphangitic carcinomatosis is the spread of metastatic disease along the lung interstitium with subsequent lymphatic obstruction, interstitial edema, and fibrosis. Primary tumors of the breast, lung, stomach, pancreas, ovary, and cervix are often associated with lymphangitic carcinomatosis. On chest radiography, the lungs may appear clear or they may show a central linear pattern of interstitial thickening that is commonly bilateral but asymmetric in distribution between the lungs. On CT, typical smooth or nodular thickening of the interlobular septa is seen often with peribronchovascular thickening and asymmetric involvement of the lungs