Localized Clinical Features that Suggest Different Types of Vasculitis

Localized Clinical Features that Suggest Different Types of Vasculitis

The below table lists features suggestive of different types of vasculitis. These features occur either before, during, or after the constitutional features and are also relatively nonspecific, with considerable overlap.

Localized Clinical Features that Suggest Different Types of Vasculitis

SymptomsDiagnosis
Jaw claudication; visual loss; palpable, thickened, tender temporal artery; or diminished temporal artery pulsationGCA
Absent radial pulses, difficulty obtaining a blood pressure in one armTakayasu arteritis or large artery involvement in GCA
Sinus involvement, otitis media, scleritisGPA (Wegener) or EGPA (Churg–Strauss syndrome)
Hypertension, renal vascular involvementPolyarteritis nodosa or Takayasu arteritis
AsthmaEGPA (Churg–Strauss syndrome)
Testicular tendernessPolyarteritis nodosa
Pulmonary–renal syndromes (hemoptysis and glomerulonephritis)GPA (Wegener) and microscopic polyangiitis
SLE and Goodpasture syndrome
Palpable purpuraCutaneous vasculitis associated with diseases causing small-vessel vasculitis

GCA, Giant cell arteritis; GPA, granulomatosis with polyangiitis; EGPA, eosinophilic granulomatosis with polyangiitis; SLE, systemic lupus erythematosus.

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