Is medical treatment available for prolactin secreting tumors? What is the mode of action?
Medical treatment with dopamine agonists has been available since the early 1980s. The most commonly used drugs are bromocriptine and cabergoline; pergolide and hydergine are also commercially available dopamine agonists, but they are not approved by the U.S. Food and Drug Administration specifically for treatment of prolactin-secreting tumors. Both bromocriptine and cabergoline are highly effective in reducing both prolactin levels and tumor size.