Is Eosinophilic Fasciitis associated with ingestion of chemicals?
EF was first described in 1974 by Dr. Lawrence Shulman and has been called Shulman’s disease. No association with ingestion of chemicals has been convincingly demonstrated. Strenuous physical exertion may precede its onset in up to 40% of patients. Notably, two similar conditions, EMS in the United States and toxic oil syndrome in Spain have been related to toxic exposures (L-tryptophan and aniline-denatured rapeseed oil, respectively).