In what situations or histopathologic diagnoses should an excisional biopsy be recommended after a percutaneous breast biopsy?
When there is histopathologic-imaging discordance, excisional biopsy should be recommended. When a high-risk lesion such as atypical ductal hyperplasia is present on histopathologic evaluation, excisional biopsy should also be recommended. When atypical ductal hyperplasia is present on percutaneous breast biopsy, cancer is present on excisional biopsy in up to 56% of cases. Other histopathologic diagnoses that should be considered for excisional biopsy include papillary lesions, radial scars, atypical lobular hyperplasia, and lobular carcinoma in situ.