Imaging Features of Blood Brain Barrier Compromise

Imaging Features of Blood Brain Barrier Compromise

What are the imaging features of BBB compromise?

• On a noncontrast computerized tomography (CT) scan, leakage of blood cells across the BBB or BCSFB is radiodense. Leakage of extracellular fluid (vasogenic edema) is radiolucent

• On a T1 contrast magnetic resonance image (MRI), leakage of blood cells across the BBB or BCSFB is hyperintense. On a T2 gradient recalled echo (GRE) sequence, leakage of blood cells across the BBB or BCSFB is hypointense. On a T2 fluid-attenuated inversion recovery (FLAIR) MRI, vasogenic edema is hyperintense