How often do migraines occur, is there associated impairment, and what are the genetics?
A quarter of all migraineurs suffer four or more severe attacks a month, 35% have one to four severe attacks per month, 38% experience one or fewer severe attacks per month, and 37% have five or more headache days per month.
In one study, during migraine attacks, most migraineurs (53.7%) reported severe impairment or the need for bed rest, whereas only 7.2% reported no attack-related impairment.
Over a 3-month period, 35.1% of the migraineurs had at least 1 day of restricted activity related to headache.
About 70% of migraineurs have an affected first-degree relative. Genetic heterogeneity is present.
