How is Tumor necrosis factor receptor associated periodic syndrome treated

How is Tumor necrosis factor receptor associated periodic syndrome treated?

  • • Prednisone during flares (tapering course over duration of flare); consider NSAIDs if mild symptoms.
  • • Etanercept is effective for many patients; some reports of success with infliximab.
  • • Both anakinra and canakinumab are effective (canakinumab is Food and Drug Administration (FDA)-approved for TRAPS).
  • • Colchicine is not effective.
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