How is occult GI bleeding usually detected

How is occult GI bleeding usually detected? 

Occult GI bleeding is typically detected by obtaining a stool sample, smearing the stool sample on a guaiac-impregnated card, and applying a reagent solution to the card. A positive test is indicated by change in the color of the impregnated card from colorless to bright blue because of the presence of peroxidase (or pseudoperoxidase) in the stool. As little as 2 to 5 mL of blood per rectum per day can produce a positive guaiac test.


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