How is Microscopic polyangiitis treated
The treatment of MPA is based on the same principles as outlined for GPA, and several randomized controlled trials studying the effects of therapeutic agents in AAV have included patients with GPA or MPA.
Owing to the serious presentation of this disease, most investigators recommend combined therapy with high-dose GCs and cyclophosphamide or rituximab. Plasmapheresis and IV gammaglobulins have been used in a few patients with progressive renal failure or pulmonary hemorrhage. Maintenance therapy is similar to GPA.
