How is HCV associated sicca syndrome different from SS

How is HCV associated sicca syndrome different from SS?

This can be difficult because patients with HCV can also produce anti-SSA and anti-SSB antibodies. However, a minor salivary gland biopsy helps to differentiate them. HCV-related sialadenitis has focal CD8 + T-cell infiltrates. In contrast, SS is characterized by the infiltration of CD4 + T cells.

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