How is chemoembolization theorized to work

How is chemoembolization theorized to work?

Embolization of tumor vessels causes ischemia. This ischemia disables tumor cell membrane ion pumps and exocytosis functions and increases capillary permeability. As a result, there is increased intracellular accumulation and dwell time of the concomitantly delivered chemotherapeutic agent, leading to increased tumor cell apoptosis.


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