How growth hormone levels normally regulated
Pituitary secretion of GH is primarily regulated by two hypothalamic hormones: stimulatory GH-releasing hormone (GHRH) and inhibitory somatostatin. Secretion of GH is also affected by adrenergic and dopaminergic hormones, as well as by other central nervous system and peripheral factors. GH is secreted from the pituitary gland in pulses and has a short plasma half-life, so GH levels can vary markedly with repeated measurements in healthy as well as disease states.
