How do women with gout differ from men with regard to disease onset and clinical features?
Compared with men, women develop gout at an older age (typically after menopause) and more often suffer from polyarticular flares. Women developing gout frequently have osteoarthritis, hypertension, and mild chronic renal insufficiency or are being treated with diuretics. Tophi developing in women are particularly common in previously damaged joints including Heberden’s nodes and in the finger pads.