How common is Focal segmental glomerulosclerosis?
Focal segmental glomerulosclerosis is a rare condition with an estimated incidence of 1.8/100,000 per year. The lifetime risk is estimated to be more than four times higher for African Americans compared with other races.
Focal segmental glomerulosclerosis is the underlying cause of approximately 4% of patients with end-stage kidney disease (ESKD) in the United States and up to 10.8% of those younger than 24 years.
In adults, Focal segmental glomerulosclerosis is the fourth most common cause of ESKD, following diabetes, hypertension, and glomerulonephritis not otherwise specified. Among children, Focal segmental glomerulosclerosis is the second leading cause of ESKD, following congenital kidney anomalies.
