How common are severe GI manifestations of polyarteritis nodosa (PAN)?
- PAN is a vasculitis that may have visceral involvement.
- GI bleeding from intestinal ischemia is seen in 6% of cases, bowel perforation in 5%, and bowel infarction in 1.4%.
- Acalculous cholecystitis occurs in up to 17% because of direct vasculitic involvement of the cystic artery and gallbladder.
