How common are acute adverse reactions to intravascular contrast material?
Acute adverse events occur in up to 0.7% of patients who receive intravascular low or iso-osmolality iodinated contrast material, and in up to 0.04% of patients who receive gadolinium-based contrast material.
Most adverse reactions to contrast agents are mild and not life-threatening, usually requiring only observation, reassurance, and/or supportive measures. Severe and potentially life-threatening adverse events occur rarely and unpredictably, most often within the first 20 minutes following contrast administration.
