What GI disease is most commonly associated with dermatitis herpetiformis?
Celiac disease (gluten-sensitive enteropathy). Although almost all patients demonstrate histologic findings of celiac disease in the gastrointestinal tract, only one-third demonstrate clinical symptoms of celiac disease. Both celiac disease and dermatitis herpetiformis respond to a gluten-free diet. Oral dapsone results in rapid improvement of the skin lesions and associated pruritus of dermatitis herpetiformis.