False negative rate of laparotomy for presumed appendicitis

When laparotomy is performed for presumed appendicitis, what is the acceptable false-negative rate? How often is another cause identified in this setting? 

A false-negative laparotomy rate of 10% to 20% is reported. 

In roughly 30% of these cases, some other cause of abdominal pain is identified, such as mesenteric lymphadenitis, Meckel’s diverticulum, cecal diverticulitis, pelvic inflammatory disease, ectopic pregnancy, or ileitis.


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