Are there extra renal manifestations of nephrotic syndrome?
Less common presentations include peritonitis.
This can even occur before the implementation of immunosuppressive therapy. In addition, thromboembolic events can complicate the course of nephrotic syndrome.
The latter complaint is much more common, at least ten fold higher, in adults.
Patients with nephrotic syndrome can present with acute kidney injury, attributable either to intra-renal edema and tubular obstruction or severe contraction of the effective intravascular compartment.
In addition, patients with unremitting nephrotic syndrome and persistent hypercholesterolemia are at risk of premature atherosclerosis and cardiovascular disease.