Endoscopic screening for CRC

When should endoscopic screening begin for individuals with a family history of CRC? How often should endoscopic surveillance be performed in these individuals? 

  • Endoscopic screening for CRC should begin at age 40 or 10 years younger than the affected relative in individuals with a first-degree relative with CRC.
  • Surveillance endoscopy should be scheduled every 3 to 5 years if the relative was younger than age of 60 at diagnosis.
  • Individuals with a first-degree relative with CRC or advanced adenomas diagnosed at age 60 years or older can be screened like average-risk persons.
  • Patients with a second- or third-degree relative with CRC should adhere to average-risk screening recommendations.
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