What's on this Page
Are other endocrine syndromes possible in patients with acromegaly or gigantism?
- Yes. Otherwise acromegaly and gigantism would not be endocrine disorders. Three endocrine syndromes include acromegaly
Endocrine Syndromes Associated with Acromegaly
| SYNDROME | MAJOR INVOLVED ORGANS | CLINICAL FINDINGS | OTHER CLUES |
| Multiple endocrine neoplasia type 1 (MEN 1) | Pituitary tumors Parathyroid hyperplasia Islet cell tumors | Hypercalcemia (most) Peptic ulcer disease (if gastrinoma) Hypoglycemia (if insulinoma) | Autosomal dominant Check calcium levels in patients with acromegaly |
| McCune-Albright syndrome | Bones Skin Gonads Others | Polyostotic fibrous dysplasia Café-au-lait spots Sexual precocity | Mostly in girls |
| Carney’s complex | Heart Skin Adrenals Others | Cardiac myomas Pigmented skin lesions | |
| Pigmented nodular adrenal hyperplasia | Many other tumors | Autosomal dominant |
