Does sickle cell disease have any rheumatologic manifestations?
| Hand–foot syndrome | • Hyperuricemia and gout |
| • Bone infarction | • Hemarthrosis |
| • Osteonecrosis of bone | • Septic arthritis |
| • Noninflammatory joint effusions adjacent to areas of bony crisis | • Osteomyelitis• Focal muscle necrosis• Rhabdomyolysis |
| • Chronic inflammation of joints | • Rhabdomyolysis |
