Which commonly prescribed hepatitis C treatment is associated with hypothyroidism?
Pegylated interferon-α2b causes or worsens underlying autoimmune thyroid disease. Hypothyroidism can be seen in upward of 5% of treated patients. In addition, tyrosine kinase inhibitors (e.g., sunitinib, imatinib), which are used to treat hepatocellular carcinoma, are also noted to cause hypothyroidism.