Does adult-type ADPCKD occur in infants and young children

Does adult-type ADPCKD occur in infants and young children?

ADPCKD has been recognized on US prenatally and postnatally. The appearance can closely mimic ARPCKD, in which both kidneys can appear large and echogenic. Small, sonographically resolvable cysts can be seen in either syndrome in the newborn period. More commonly, ADPCKD is suspected if US reveals progressive development of multiple cortical and medullary renal cysts; this may be found incidentally or in a child referred for hypertension and hematuria. Careful examination of the family history and US screening of the family are recommended to detect any evidence of cystic kidney disease in parents who may be unaware of their own subclinical disease.


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