Differential Diagnosis of Salivary Gland Enlargement
| Usually unilateral | ||
| Bacterial infection | Chronic sialadenitis | Lymphoma |
| Obstruction | Primary salivary gland neoplasms | |
| Usually bilateral (asymmetric) | ||
| Granulomatous diseases | HIV/Diffuse infiltrative lymphocytosis syndrome (HIV-Associated Rheumatic Syndromes) | IgG4-related disease (may be massive) |
| Recurrent parotitis of childhood | Viruses (mumps, cytomegalovirus, influenzae, coxsackie A) | |
| Bilateral (symmetric) | ||
| Acromegaly | Alcoholism | Anorexia/bulimia |
| Chronic pancreatitis | Diabetes mellitus | Gonadal hypofunction |
| Hepatitis cirrhosis | Hyperlipoproteinemia | Idiopathic |
