CT and MRI features of adrenal hyperplasia

What is adrenal hyperplasia, and what are its CT and MRI features?

Adrenal hyperplasia refers to nonmalignant proliferation of adrenal cortical cells. It may be symptomatic secondary to hormonal hyperfunction of the adrenal glands (such as in the setting of Conn’s syndrome or adrenocorticotropic hormone [ACTH]-dependent Cushing’s syndrome), or it may be asymptomatic.

On CT and MRI, smooth diffuse adrenal gland thickening or adrenal gland multinodularity with maintenance of the normal inverted-Y or inverted-V configuration is typically seen, most often involving the adrenal glands bilaterally. However, the adrenal glands may sometimes have a normal appearance.


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