Critical illness polyneuropathy (CIP)

Critical illness polyneuropathy (CIP)

Intensive care unit (ICU)-acquired weakness are a group of neuromuscular disorders commonly affecting patients with critical illnesses. CIP is most likely to occur in patients with severe sepsis, multiple organ dysfunction, and those receiving prolonged mechanical ventilation (26% to 65% of patients on ventilator for >5 to 7 days).

Manifestations include limb muscle weakness, reduced or absent deep tendon reflexes, loss of distal sensation, and respiratory insufficiency due to phrenic nerve involvement.

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