Conditions which affect the lower motor neuron
What other conditions primarily affect the lower motor neuron (anterior horn cell)?
The differential diagnosis of deficits primarily confined to the anterior horn cell (AHC) includes several inherited diseases such as X-linked bulbospinal muscular atrophy and proximal spinal muscular atrophy.
Acquired lower motor neuron syndromes including poliomyelitis, postpolio syndrome, progressive muscular atrophy, and AHC degeneration in other conditions (e.g., CJD) also need to be considered.