Causes of matched ventilation and perfusion defects on a ventilation perfusion scan

What are the causes of matched ventilation and perfusion defects on a ventilation perfusion scan?

Most conditions associated with matched ventilation and perfusion defects arise from diseases affecting the airways with subsequent physiologic shunting of blood away from the underventilated regions. The most common causes of matched defects include COPD, bronchiectasis, and asthma. Other causes include pleural effusions, mucous plugging, tumors, and pneumonia.

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