Breast Cancer Tumor Analysis

Breast Cancer Tumor Analysis- Why am I having this test?

Breast Cancer Tumor Analysis test is used to determine the likelihood that your breast cancer will return after the tumor has been removed. This test also helps to determine any future treatment.

What kind of sample is taken?

This test is done using a biopsy of the breast tumor tissue.

How do I prepare for this test?

Talk to your health care provider about any necessary preparation. He or she will give directions as needed.

What are the reference ranges?

Reference ranges are considered healthy ranges established after testing a large group of healthy people. Reference ranges may vary among different people, labs, and hospitals. It is your responsibility to obtain your test results. Ask the lab or department performing the test when and how you will get your results.

What do the results mean?

Normal values include:

  • DNA ploidy: Diploid is favorable.
  • S-phase fraction: Less than 5.5% is favorable.
  • HER 2 protein:
    • IHC method: 0 to 1+.
    • FISH method: Less than 2 copies per cell.
    • OncoType Dx Method: Less than 10.7 units.
  • Cathepsin D: Less than 10% is favorable.
  • p53 protein: Less than 10% is favorable.
  • Ki67 protein:
    • 10–20% is borderline.
    • Less than 20% is favorable.

If your results are outside of favorable ranges, this means that tumor markers are present in higher quantities. This may indicate a more aggressive cancer and a higher risk of recurrence.

Talk with your health care provider to discuss your results, treatment options, and if necessary, the need for more tests. Talk with your health care provider if you have any questions about your results.

Talk with your health care provider to discuss your results, treatment options, and if necessary, the need for more tests. Talk with your health care provider if you have any questions about your results.

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