Biomarkers to diagnose immunoglobulin a nephropathy
Are there any biomarkers to diagnose immunoglobulin a nephropathy or monitor the activity of the disease?
Not yet. Although increased levels of serum IgA can be found in up to 50% of cases, this finding is not specific and has no diagnostic or prognostic value.
Alternative biomarkers have been identified, including serum galactose-deficient IgA1 (GD IgA1) and GD IgA1 antibodies and immune complexes, but their utility in routine clinical practice has not been established.
