What are the benefits of metabolic acidosis?
It should also be recognized that there may be benefits from metabolic acidosis. Most importantly, the Bohr effect leads to a shift of the hemoglobin-O 2 dissociation curve to the right, leading to more unloading of O 2 to tissues. Whatever adverse effects occur as the result of acidosis, treatment of metabolic acidosis is not necessarily beneficial, particularly when acute. Administration of sodium bicarbonate may not lead to the expected benefit and can itself lead to adverse effects.